Tag: therapeutic index

10 Mar 2026
by Michael Brown
14 Comments

Prescriber Attitudes Toward NTI Drugs and Substitution: What Doctors Really Think

Prescribers remain cautious about substituting generic versions of narrow therapeutic index (NTI) drugs due to risks of toxicity or therapeutic failure. Despite FDA assurances, doctors, pharmacists, and patients face real-world challenges in ensuring safety and stability.